Summer 2023 Newsletter
See What We’ve Been Up To Lately
Since our last newsletter, two major conferences have come and gone. We attended CYTO 2023 and ISEV 2023 (the annual meeting of the International Society of Extracellular Vesicles). I want to share with you some of what we’ve been up to during that time.
One of the most exciting things we’ve been doing is spreading the word on our latest innovation, the Delaware Flow NanoCytometer™. This is our custom designed analyzer for ultrasensitive detection of nanoparticles such as extracellular vesicles—without compromising its ability to perform more standard cell-based flow cytometry, making it a dual use workhorse for your core lab.
We’ve also had some good news from the USPTO, made some improvements to our website, and welcomed another new team member.
Scroll down to see more about what we’ve been doing lately.
All the best,
Giacomo
Latest Update
The Delaware Flow NanoCytometer™
If you don’t know, the Delaware is our latest instrument that provides dual-use capability for cell and nanoparticle researchers alike. Our new brochure has all the latest performance data from the Delaware.
The Delaware offers:
- At least 60 nm sensitivity for nanoparticle detection
- Up to 5 lasers and 6 fluorescence detection channels
- Up to 3 scattering channels
- Dual use for cells AND nanoparticles
- Ease of use
You can also read more about the Delaware, including full instrument specs, on our website.
The Delaware – see what you’ve been missing.
Conferences and Talks
Kinetic River Features Delaware at ISEV
For the first time, Kinetic River attended the annual meeting of the International Society of Extracellular Vesicles (ISEV 2023). We were very proud to be a Bronze Sponsor of ISEV and were excited to bring our Delaware Flow NanoCytometer™. It was fantastic to interact with the amazing community of extracellular vesicle researchers.
The Delaware was custom designed to meet the demanding needs of nanoparticle researchers, offering up to three scatter channels for sensitivity to at least 60 nm. With up to five high-powered lasers and six sensitive fluorescence channels, the Delaware provides dual-use capability, enabling more traditional cell-based flow cytometry or sensitive fluorescence detection for more comprehensive analysis of nanoparticles—all in the same instrument. Not only that, the Delaware, with its intuitive instrument control and data visualization software, provides you with the ease of use you have been missing in your nanoparticle research.
At the show, we presented loads of our latest Delaware data in our poster “Ultrasensitive Nanoparticle Detection with the Delaware Flow NanoCytometer™.”
Kinetic River at CYTO 2023
Even though it overlapped with the ISEV meeting, Kinetic River would never miss CYTO. We were busy moving between ISEV in Seattle and CYTO in Montréal, but we were able to be at both.
At CYTO, in addition to our poster highlighting our latest Delaware data, we presented a poster on the Colorado, our analyzer which provides automated removal of autofluorescence. The poster, “Progress Towards Real-Time Automated Autofluorescence Removal in a 16-Color Flow Cytometer,” shared our latest results.
The Colorado uses our proprietary Time-Resolved Flow Cytometry (TRFC) technology to achieve this feat. If you’re curious about how we do this and more with TRFC, you can download our Freedom Flow® brochure.
Free yourself from autofluorescence with the Colorado
Virtual Talk at Italian Cytometry Society
As if being at both ISEV and CYTO was not enough, Kinetic River Founder and President Dr. Giacomo Vacca not only attended both conferences, but he also gave a virtual remote talk (in Italian!) to the 41st National Cytometry Conference in Naples Italy. The talk, entitled “Delaware Flow NanoCytometer™: Ultrasensitive Detection of Nanoparticles” discusses the capabilities of the system in the analysis of nanoparticles, including exosomes and extracellular vesicles.
We are so pleased to be able to spread the word about this much needed tool for nanoparticle researchers so widely.
Latest Kinetic River Happenings
Two New Patents Allowed
Kinetic River was recently issued two new patents:
- U.S. Patent No. 11,573,167 “Flow Cytometry Apparatus and Methods.”
- U.S. Patent No. 11,635,384 “Methods and Apparatuses for Label-Free Particle Analysis.”
These are our fifth and sixth patents issued since December, making 21 overall (19 U.S. patents, one in China and one in Japan).
‘167 further broadens our patent portfolio in the field of extreme throughput cytometry, and ‘384 addresses the field of label-free flow cytometry and particle analysis.
For reference, our patents fit into the following families of intellectual property:
- Time-resolved technologies, including the Arno (compensation-free flow cytometry), Danube (direct fluorescence lifetime measurements) instruments, Colorado (automated autofluorescence removal), and Tiber (label-free cancer cell detection).
- Extremely high-throughput flow cytometry (Loire).
- Label-free flow cytometry (Yangtze).
- Modular, customizable systems (Potomac and Delaware).
Kinetic River’s Founder and President, Dr. Giacomo Vacca now holds 71 patents (with more on the way). See his full list of patents in his bio.
We owe a tremendous debt of gratitude to Ashley R. Sloat, Ph.D. and Aurora Consulting LLC for their outstanding work on developing and expanding our patent portfolio.
Two New Trademarks Allowed
More good news from the USPTO. Two of our trademarks have recently been allowed.
The first is our new tagline, “Where Light Meets Life.” We love this tagline since this is exactly how the magic happens inside the flowcell when the laser hits the cells. Kinetic River Founder and President Dr. Giacomo Vacca says “Can’t think of a better tagline for flow cytometers!!! I came up with this many years ago and never got around to filing it. Finally I decided to go for it.”
See how our innovative flow cytometry products all embody this slogan on our product page.
The other is for “Freedom Flow,” our platform of instruments, currently under development, that consists of the Arno, for compensation-free flow cytometry, the Colorado, for autofluorescence-free flow cytometry, and the Tiber, for label-free flow cytometry. Freedom Flow® also paves the way toward 40+ color flow cytometry.
At the core of Freedom Flow is our proprietary Time-Resolved Flow Cytometry (TRFC) technology. Listen to Dr. Giacomo Vacca explain TRFC in this brief video.
Meet the Kinetic River Team
We’ve recently updated the Our Team page on our website. Check it out to see the amazing group of employees, advisors, and partners we have, including the latest additions to the team.
We are so grateful to all of them for helping us do what we do.
Employee Spotlight
Kinetic River Welcomes Kennan LaneLutter
Kinetic River welcomes Lab Tech Kennan LaneLutter. Kennan received his BS from the University of California, Santa Cruz. He has spent over 10 years in the biotech field, including medical devices and diagnostics. He brings experience in rare cell isolation as part of his work contributing to the development of non-invasive prenatal test methods.
At Kinetic River, Kennan will be a key contributor to many of our ongoing flow cytometry instrument development projects.
Welcome, Kennan!
Stay Updated on LinkedIn
Do you have a LinkedIn account? If so, we would like to keep you updated via that channel as well.
To start following our LinkedIn posts, you can click + Follow on the Kinetic River page.
Get Our Next Newsletter in Your Inbox
Stay in the loop with Kinetic River via our newsletter.
