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Founder's Profile

Giacomo Vacca, Ph.D.

Volwiler Research Fellow
OSA Senior Member
SPIE Senior Member

Giacomo Vacca earned his B.A. and M.A. in Physics from Harvard University, and his Ph.D. in Applied Physics from Stanford University. His dissertation, under the guidance of Nobel Prize winner Bob Laughlin, introduced a new ultrafast optical technique for investigating microscopic fluid phenomena.

Dr. Vacca’s career spans the life sciences, in vitro diagnostics, microfluidics, lasers, telecommunications, and the energy sector, including 26 years of experience in research and development and other functional roles. He has set up whole laboratories from scratch, started and led development projects, managed large multifunctional groups, generated intellectual property (40 patents issued, 29 pending) and managed IP portfolios. A breakthrough technology he conceived and developed, Laser Rastering, boosted flow cytometry analysis throughput by a factor of 30. Among the products he helped develop and bring to market are flow cytometers, hematology analyzers, solid-state lasers, and integrated waveguide optical components.

Dr. Vacca has served as an expert witness, including testifying under deposition, in patent invalidity cases and other litigation in the fields of flow cytometry, cell sorting, particle analysis and particle separation.

Awards & Honors

Elite Expert
IMS Expert Services, 2017

Senior Member
International Society
for Optics and Photonics, 2015

Research Fellow
Volwiler Scientific Society
Abbott Laboratories, 2010

Senior Member
Optical Society of America, 2010

Top Research Platinum Award
for Laser Rastering
Abbott Hematology, 2009

Silver Award
for Outstanding Technical Leadership
Abbott Hematology, 2009

Technical Leadership Award Nominee
Abbott Diagnostics
Technical Advisory Board

Abbott Laboratories, 2008

Patents Issued to Dr. Vacca

U.S. patent # 10,094,761
Flow cytometry apparatus and methods

U.S. patent # 9,952,133
Particle analysis and sorting apparatus and methods

U.S. patent # 9,933,349
Method for determining volume and hemoglobin content of individual red blood cells

European patent # 2,470,881
Method for flagging a sample

U.S. patent # 9,810,618
Basophil analysis system and method

U.S. patent # 9,797,824
Method for hematology analysis

U.S. patent # 9,778,193
Methods and apparatuses for label-free particle analysis

U.S. patent # 9,778,163
Nucleated red blood cell analysis system and method

U.S. patent # 9,978,162
White blood cell analysis system and method

Japanese patent # 6,166,716
Basophils analysis system and method

Chinese patent # 103,975,054
Nucleated red blood cell analysis system and method

U.S. patent # 9,671,326
Flow cytometry apparatus and methods

U.S. patent # 9,658,148
Particle analysis and sorting apparatus and methods

U.S. patent # 9,638,621
Method for discriminating red blood cells from white blood cells by using forward scattering from a laser in an automated hematology analyzer

U.S. patent # 9,618,498
Method for flagging a sample

Chinese patent # 103,987,834
White blood cells analysis system and method

Japanese patent # 6,104,233
White blood cells analysis system and method

U.S. patent # 9,551,645
Flow cytometry apparatus and methods

Japanese patent # 6,029,657
Nucleated red blood cell analysis system and method

Chinese patent # 103,917,868
Basophils analysis system and method

Japanese patent # 5,871,792
In automated hematology analyzers, by using a forward scatter from a laser, a method to determine the red blood cells from white blood cells

U.S. patent # 9,267,931
Method for discriminating red blood cells from white blood cells by using forward scattering from a laser in an automated hematology analyzer

U.S. patent # 9,261,515
Method for determining volume and hemoglobin content of individual red blood cells

U.S. patent # 9,261,495
Method for flagging a sample

Chinese patent # 102,933,964
A method for measuring the volume and hemoglobin content of individual red blood cells

U.S. patent # 9,103,759
Nucleated red blood cell analysis system and method

U.S. patent # 9,097,704
Method for hematology analysis

U.S. patent # 9,091,625
Basophil analysis system and method

U.S. patent # 9,091,624
White blood cell analysis system and method

U.S. patent # 8,911,669
Method for flagging a sample

U.S. patent # 8,906,309
Method for discriminating red blood cells from white blood cells by using forward scattering from a laser in an automated hematology analyzer

U.S. patent # 8,906,308
Method for determining volume and hemoglobin content of individual red blood cells

U.S. patent # 8,715,572
Method and apparatus for detection, analysis, and collection of rare cellular events

Japanese patent # 5,465,180
Count and identification methods and apparatus for high-speed biological particles in the flow

Japanese patent # 5,457,560
A method for attaching a flag to a sample

Japanese patent # 5,226,007
Method and apparatus for rapidly counting identify suspended particles by scanning

U.S. patent # 8,400,632
Method and apparatus for rapidly counting and identifying biological particles in a flow stream

U.S. patent # 8,253,938
Method and apparatus for rapidly counting and identifying biological particles in a flow stream

U.S. patent # 8,159,670
Method and apparatus for rapidly counting and identifying biological particles in a flow stream

U.S. patent # 8,045,162
Method and apparatus for rapidly counting and identifying biological particles in a flow stream

U.S. patent # 7,804,594
Method and apparatus for rapidly counting and identifying biological particles in a flow stream

U.S. patent # 7,283,696
Microfluidic control for waveguide optical switches, variable attenuators, and other optical devices

U.S. patent # 7,016,560
Microfluidic control for waveguide optical switches, variable attenuators, and other optical devices

U.S. patent # 6,949,176
Microfluidic control using dielectric pumping

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