December 2023 Newsletter
See What We’ve Been Up To Lately
Since our last newsletter, we’ve been spreading the word on our latest innovation, the Delaware Flow NanoCytometer™. The Delaware is our custom designed analyzer for ultrasensitive detection of nanoparticles such as extracellular vesicles—without compromising its ability to perform more standard cell-based flow cytometry, making it a dual use workhorse for your core lab. Not only have we signed a major agreement improving our ability to reach the nanoparticle research community, but we have also demonstrated outstanding resolution on the system.
We’ve also had some good news on the patent front and have posted some photo galleries from our travels.
Scroll down to see more about what we’ve been doing lately.
All the best,
Giacomo
Latest Updates
6-nm Resolution on the Delaware
If you don’t know, the Delaware is our latest instrument flow cytometry instrument providing dual-use capability for cell and nanoparticle researchers alike. It is designed for ultrasensitive detection of nanoparticles including exosomes and other extracellular vesicles, without compromising ease of use or the ability to perform more standard cell analysis.
Download our latest Tech Note demonstrating an estimated 6-nm resolution. See more of our latest performance data from the Delaware in our new brochure.
The Delaware offers:
- At least 28-nm sensitivity for nanoparticle detection
- An estimated 6-nm resolution
- Up to 5 lasers and 6 fluorescence detection channels
- Up to 3 scattering channels
- Dual use for cells AND nanoparticles
- Ease of use
The Delaware – see what you’ve been missing.
Kinetic River Inks Sales Agreement
We are thrilled to announce that Kinetic River has entered into agreements with six sales organizations across North America to represent our Delaware Flow NanoCytometer.
Precision Particle Measurements, New England Analytical Instruments, LB Technologies, NanoBio Systems, Nanostars, and E=hv will sell the Delaware Flow NanoCytometer throughout North America. “This joint effort will enable us to reach much further and deeper than we could on our own,” said Dr. Giacomo Vacca, Kinetic River president and CEO.
According to Gary Linz, CEO of Precision Particle Measurements, one of the sales organizations involved, “Kinetic River has developed the perfect complement to Particle Metrix’s Nanoparticle Tracking Analysis (NTA) capabilities. The Delaware flow cytometer is an important addition to the field of EV/exosome characterization.”
Read the full press release here →
Conferences and Talks
Kinetic River Speaks at NIH
Kinetic River was invited to speak at the 2023 NIH Flow Cytometry Interest Group Meeting on September 12 in Bethesda, MD. We also had a booth in the exhibit hall where we showed off the Delaware Flow NanoCytometer and its nanoparticle analysis capabilities.
During the talk, we presented the latest data from the Delaware showing, among other things, 22-nm resolution (more recent data indicates an estimated 6-nm resolution) on polystyrene nanoparticles and the fluorescence sensitivity required to see relevant tetraspanin markers on extracellular vesicles.
Many thanks to the organizers Kathy McKinnon, Mehrnoosh Abshari, and Bill Telford at NIH for putting together a great meeting and giving us the opportunity to speak.
Kinetic River Sponsors Italian Extracellular Vesicle Symposium
Kinetic River was proud to be an exhibitor and a silver sponsor at the Third Annual Symposium of the Italian Society of Extracellular Vesicles (EVIta). Dr. Vacca and our colleagues at CytoFlow Service spent the conference discussing the latest data from our Delaware Flow NanoCytometer with all who were interested.
The symposium was held September 13–15, 2023 in Urbino Italy.
View our photos from the event →
Find out more about our Delaware →
Kinetic River Sponsors Meeting on Intercellular Communication
Kinetic River was proud to be an exhibitor and a bronze sponsor at the Third Annual Meeting of the American Society for Intercellular Communication (ASIC). The program included the functions of extracellular vesicles in cancer, CNS diseases, infections (both bacterial and viral), the mechanistic basis for their biogenesis and activities, and technological and diagnostic advances in the field.
Dr. Vacca discussed the latest data from the Delaware with all who stopped by the booth.
The three-day symposium was held October 12–14, 2023 in Potomac, MD.
Kinetic River Takes the Delaware on the Road
Kinetic River presented at SelectBio’s Extracellular Vesicles & Cell-Free RNAs 2023 conference. President and CEO Dr. Giacomo Vacca talked about the Delaware and its capabilities in a talk entitled “Ultrasensitive EV Detection by Flow Cytometry.”
We also were able to bring the Delaware with us, where it was available in the Demo Room to all who were curious and wanted an up-close look.
The meeting took place November 28–30 in Laguna Hills, CA.
Latest Kinetic River Happenings
Kinetic River Achieves Two Patent Milestones
Kinetic River was recently issued two new patents:
- U.S. Patent No. 11,740,174 “Apparatus and Methods for Particle Analysis and Autofluorescence Discrimination”
- Canadian Patent No. 2,954,163 “Flow Cytometry Apparatus and Methods”
These represent our milestone 20th U.S. patent and our first patent allowed in Canada. This brings the count up to 23 overall (20 U.S. patents, and one each in China, Japan, and Canada). The ‘174 ‘ further broadens our patent portfolio in the field of time-resolved flow cytometry and the ‘163 addresses extreme throughput cell/particle analysis and sorting.
For reference, our patents fit into the following families of intellectual property:
- Time-resolved technologies, including the Arno (compensation-free flow cytometry), Danube (direct fluorescence lifetime measurements) instruments, Colorado (automated autofluorescence removal), and Tiber (label-free cancer cell detection)
- Extremely high-throughput flow cytometry (Loire)
- Label-free flow cytometry (Yangtze)
- Modular, customizable systems (Potomac, Delaware, and Cavour)
Kinetic River’s Founder and President, Dr. Giacomo Vacca now holds 77 patents (with more on the way). See his full list of patents in his bio.
We owe a tremendous debt of gratitude to Ashley R. Sloat, Ph.D. and Aurora Consulting LLC for their outstanding work on developing and expanding our patent portfolio.
New Photo Galleries on Website
We recently uploaded three new photo galleries to the Kinetic River website.
We had a blast at our first visit to ISEV 2023 (the annual meeting of the International Society for Extracellular Vesicles) in Seattle this summer. We took a lot of pictures and have added two new photo galleries to our website – one dedicated to the ISEV show and another to our sightseeing around Seattle.
Check out our photos from ISEV →
On the heels of ISEV, we hurried off to Montreal for CYTO 2023 (the annual meeting of the International Society for Advancement of Cytometry). We have pictures from the conference and also our excursions around the city.
Check out our photos from CYTO →
Finally, we couldn’t help but take in the sights in beautiful Urbino, Italy during the Third Annual Symposium of the Italian Society of Extracellular Vesicles (EVIta). Dr. Vacca and our colleagues at CytoFlow Service manned the booth and Giacomo was happy to be back in his native country.
Check out our photos from EVIta →
Stay Updated on LinkedIn
Do you have a LinkedIn account? If so, we would like to keep you updated via that channel as well.
To start following our LinkedIn posts, you can click + Follow on the Kinetic River page.
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