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Selected Publications

“Compensation-Free Flow Cytometry Based on Fluorescence Lifetime”

G. Vacca, K.P. Shevgaonkar, R. Jimenez, D. Vacca, A. Singhal, R. McKay, D. Schodin

Oral Presentation, CYTO 2018 (May 2018)

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Tags: flow cytometry, compensation, spectral spillover, spectral crosstalk, fluorescence lifetime, multiplexing, multicolor flow cytometry

“More Robust Fluorescence Lifetime Measurements for Cell Biology and Multiplexing”

G. Vacca, K.P. Shevgaonkar, R. Jimenez, A. Singhal, D. Vacca, D. Schodin, R. McKay

Poster Presentation, CYTO 2018 (May 2018)

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Tags: flow cytometry, fluorescence lifetime, multiplexing, Förster Resonance Energy Transfer, FRET

“An Open Architecture Analyzer for Flow Cytometry Technology Development”

W. Telford, V. Kapoor, N.V. Hawk, G. Vacca

Oral Presentation, CYTO 2017 (June 2017)

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Tags: flow cytometry, modularity, Potomac, flexible instrumentation, custom flow cytometers

“A Modular Platform for Flexible Flow Cytometry”

G. Vacca, K.P. Shevgaonkar, N.V. Hawk, V. Kapoor, W. Telford

Poster Presentation, CYTO 2017 (June 2017)

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Tags: flow cytometry, modularity, Potomac, flexible instrumentation, custom flow cytometers

“Flow Cytometry Pushes the Envelope of Applications Possibilities”

G. Vacca

Laser Focus World (June 2017)

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Tags: flow cytometry, multiplexing, multicolor flow cytometry, Arno, fluorescence lifetime, Danube, modularity, Potomac, AIDS, CD4 testing, hematology, miniaturization, immunology, high sensitivity, extracellular vesicles, nanoparticles

“Software Environment Creates Coherent Workflow for Optical System Design”

G. Vacca, S. Murphy, T. Karras, H. Lehtimäki

Laser Focus World (May 2017)

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Tags: system modeling, optical system design, design automation, biophotonic instrumentation, flow cytometer design, virtual prototyping, 3D CAD modeling

“The Bootstrap Advantage: Why Start Ups are Nixing the VC World”

Featured in article and interview by G. Spieler

Geri Spieler’s Blog, 28 November 2016

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Tags: startups, bootstrapping, flow cytometry, Excelitas Technologies, Sean Murphy

“In Vitro Diagnostics, Immunology Spurring Advances in Flow Cytometry”

G. Vacca

Photonics Spectra (November 2016)

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Tags: flow cytometry, portable instrumentation, field use, infectious diseases, AIDS, CD4 testing, hematology, multiplexing, immunology, high sensitivity, extracellular vesicles, nanoparticles

“Instrumentation Advances Add Flexibility and Quantitation to Flow Cytometry”

G. Vacca and J. P. Houston

BioOptics World (January 2015)

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Tags: flow cytometry, fluorescence lifetime, Förster Resonance Energy Transfer, FRET, multiplexing

“Lessons Learned in Biophotonic Systems Design”

G. Vacca

Biophotonics (October 2014)

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Tags: system simulation, parametric modeling, optical system design, design automation, biophotonic instrumentation, flow cytometer design, virtual prototyping, 3D CAD modeling, virtual optics bench

“3 Questions With Dr. Giacomo Vacca, Kinetic River Corp.”

Article and interview by S. Tracy

Biophotonics (May 2014)

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Tags: flow cytometry, fluorescence lifetime, FRET, biophotonic system design, design automation, virtual optics bench

“Fluorescence Lifetime Excitation Cytometry by Kinetic Dithering”

W. Li, G. Vacca, M. Castillo, K. D. Houston, J. P. Houston

Electrophoresis. doi: 10.1002/elps.201300618 (2014)

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Tags: flow cytometry, fluorescence lifetime, fluorescence decay, time-resolved, bioanalytical

“Automated Design for Biophotonic Systems”

G. Vacca, H. Lehtimäki, T. Karras, S. Murphy

Proc. SPIE 8992, 899202 (2014)

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Tags: system simulation, parametric modeling, optical system design, design automation, biophotonic instrumentation, flow cytometer design, virtual prototyping, 3D CAD modelinga

“Flow Cytometry Expands Application Range”

Featured in article and interview by C. Shaffer

Genetic Engineering and Biotechnology News 30, 26 (15 November 2010)

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Tags: flow cytometry, hematology, cellular analysis, laser rastering, high throughput screening

“Laser Rastering Flow Cytometry: Fast Cell Counting and Identification”

G. Vacca, M. R. Junnarkar, N. R. Goldblatt, M. W. Yee, B. M. Van Slyke, and T. C. Briese

Proc. SPIE 7182, 71821T (February 2009)

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Tags: flow cytometry, hematology, cellular analysis, laser rastering, light scattering, fluorescence, acousto-optic deflector, digital signal processing

“Breathing New Life Into Biomedical Markets: The Story of Arcturus Bioscience”

G. Vacca

Optics and Photonics News (March 2007)

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Tags: laser capture microdissection, genomic analysis, gene expression, tumor biopsy

“Moving Solid-State Cyan Lasers Beyond 20 mW”

G. M. H. Knippels, S. Koulikov, B. Kharlamov, G. Vacca, C. W. Rella, B. A. Richman, A. A. Kachanov, S. Tan, E. H. Wahl, H. Pham, and E. R. Crosson

Proc. SPIE 5332, 175 (2004)

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Tags: solid-state lasers, external cavity lasers, blue lasers, 488 nm lasers, frequency conversion, SHG, PPKTP

“Differential Light Scattering: Probing the Sonoluminescence Collapse”

G. Vacca, R. D. Morgan, and R. B. Laughlin

Physical Review E 60, R6303 (1999)

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Tags: sonoluminescence, bubble dynamics, Ti:sapphire amplifier, light scattering, Mie scattering, ultrafast gating, polarization

“Si/Ge Films on Laterally Structured Surfaces: An X-ray Study of Conformal Roughness”

M. Tolan, G. Vacca, S. K. Sinha, Z. Li, M. H. Rafailovich, J. Sokolov, H. Lorenz, and J. P. Kotthaus

Appl. Phys. Lett. 68, 191 (1996)

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Tags: thin films, silicon, germanium, structured substrates, conformal roughness, X-ray scattering, SAXS, Fourier analysis

“Thin Polymer Films on Rough Surfaces”

M. Tolan, G. Vacca, J. Wang, S. K. Sinha, Z. Li, M. H. Rafailovich, J. Sokolov, A. Gibaud, H. Lorenz, and J. P. Kotthaus

Physica B 221, 53 (1996)

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Tags: thin films, polymers, structured substrates, conformal roughness, X-ray scattering, SAXS, Fourier analysis

“X-ray Diffraction from Mesoscopic Systems: Thin Films on ‘Rough’ Surfaces”

M. Tolan, G. Vacca, S. K. Sinha, Z. Li, M. H. Rafailovich, J. Sokolov, H. Lorenz, and J. P. Kotthaus

J. Phys. D: Appl. Phys. 28, A231 (1995)

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Tags: thin films, polymers, structured substrates, conformal roughness, X-ray scattering, SAXS, Fourier analysis

“X-ray Scattering Studies of Molecular Ordering Phenomena in Confined Films”

S. K. Sinha, M. Tolan, G. Vacca, Z. Li, M. H. Rafailovich, J. Sokolov, H. Lorenz, J. P. Kotthaus, Y. P. Feng, G. Grubel, and D. Abernathy

Mat. Res. Soc. Symp. Proc. 366, 3 (1995)

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Tags: thin liquid films, structured substrates, conformal roughness, X-ray scattering, SAXS, Fourier analysis

“Annealing Effects and Signatures of the Order-Disorder Transition in Block Copolymer Cylinders”

D. Perahia, G. Vacca, S. S. Patel, H. J. Dai, and N. P. Balsara

Macromolecules 27, 7645 (1994)

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Tags: block copolymers, order-disorder transition, X-ray scattering, SAXS

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