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Spring 2021 Newsletter

Spring 2021 Newsletter

From CYTO 2021 to the Cavour’s Debut

Here at Kinetic River we are eager for this year’s CYTO Virtual Interactive conference, hosted by ISAC.

To see a preview of what our team will present at the CYTO conference and catch up with the latest news from Kinetic River, scroll down and enjoy this edition of our newsletter.

We look forward to seeing everyone at CYTO!

Kinetic River at CYTO 2021

A Sneak Peek of Our Posters

“Applications of Time-Resolved Flow Cytometry”
Kinetic River has brought time-resolved measurements to flow cytometry. Previously used for static measurements in Fluorescence Lifetime Imaging Microscopy (FLIM), lifetime measurements can now be done in the high-throughput realm of flow. See what novel applications this enables.
Download the poster here →

“Compensation-Free Flow Cytometry”
Tired of performing compensation in your flow cytometry experiments? Hear how we built an analyzer capable of 12-color, compensation-free operation when we present this poster.
Download the poster here →

“Automated Elimination of Autofluorescence Interference in Flow Cytometry”
How do you deal with cellular autofluorescence in your flow cytometry experiments? Find out how we can remove unwanted autofluorescence signal without altering your workflow or adding unnecessary steps to your protocol.
Download the poster here →

“Triple-UV/Violet Excitation Analyzer for Label-Free Flow Cytometry”
If you have unusual flow cytometry instrumentation needs, then our modular Potomac instrument could be the right solution for you. In this poster, we will present results from a custom-built Potomac designed for an uncommon 266-nm deep UV laser.
Download the poster here →

“Label-Free Flow Cytometric Measurements of Cellular Metabolic Factors for Detection of Cancer Cells”
See what can you do with time-resolved flow cytometry in the field of cancer research. In this poster, we will show you how our instruments can enable simple, label-free cancer cell discrimination.
Download the poster here →

“A Highly Customizable Fluidics Control Module for Flow Cytometry”
Designed to address unique fluidics needs in your flow cytometry experiments, or to simply provide ultrastable flow for your existing instrument, the Shasta is our completely customizable fluidics module.
Download the poster here →

“An Always-On Remote Flowcell Monitoring Module”
Do you need to know exactly what is going on inside your flowcell? We show you our flowcell monitoring system, the Cavour, which enables you to monitor your system remotely without removing the cover. This can simplify troubleshooting, allowing you to fix problems yourself and avoid unnecessary service calls.
Download the poster here →

Kinetic River News

Meet Our All-New Flowcell Monitoring Module, the Cavour

We’re thrilled that one of our latest innovations is now ready to put into your hands. Meet the Cavour, our all-new Flowcell Monitoring Module.

The Cavour allows you to monitor your system remotely without removing the cover.

  • Simplify troubleshooting of common fluidics issues
  • Verify laser status, monitor flow stability, align laser and sample stream, and set core stream dimensions
  • Avoid unnecessary service calls and reduce system downtime

The Cavour architecture is compatible with most commercial flow cytometry systems, with a version for the BD FACSCalibur™ already released and several more in development.

Take control of your flow cytometer’s performance, and let your system reach its full potential.

See the Cavour’s specifications and learn more →

Kinetic River Completes NIH Phase I SBIR Project

We recently completed an NIH Phase I SBIR project funded by the National Institute of General Medical Sciences (NIGMS).

The study successfully demonstrated the removal of the contribution of autofluorescence signal in flow cytometry using our patented and proprietary time-resolved methods.

Further development of this instrument, dubbed the Colorado, will result in the commercialization of a 4-laser, 16-channel instrument with fully automated autofluorescence removal.

A quote from our Founder and President, Dr. Giacomo Vacca, via the press release:

“We are thrilled to have hit all of our milestones. Through a combination of hardware and algorithm development, we have been able to demonstrate the removal of the autofluorescence contribution from a population of exogenously stained eosinophils—a cell type with notoriously high autofluorescence signal. The ability to get cleaner signals from such cells will ultimately lead to higher quality data without altering the end-user workflow. We are grateful to NIGMS and the SBIR program for affording us this opportunity.”

Read the press release and see some of our results →

Kinetic River Featured in Photonics Spectra

As researchers study the immune system’s response to the SARS-CoV-2 virus amidst the COVID-19 pandemic, flow cytometry has played an integral role in their investigation.

In the March 2021 edition of Photonics Spectra, our Founder and President, Dr. Giacomo Vacca, and Kinetic River customer Dr. William Telford, from the National Cancer Institute at NIH, discuss the topic.

The article, “Flow Cytometry Channels Photonics to Advance Immunology,” was written by Farooq Ahmed and covers the rapid evolution of the field, and its role in unraveling the mysteries of the immune response, nanoscale flow cytometry, and the promise of fluorescence lifetime flow cytometry.

Read the article →

Kinetic River is Issued its 11th Patent

Kinetic River was recently issued U.S. Patent No. 10,955,330, “Particle Analysis and Sorting Apparatus and Methods.”

This is our company’s eleventh issued patent (ten in the U.S. and one in China), and it further broadens our patent portfolio in the field of time-resolved flow cytometry.

Our patents fall into four different families of intellectual property:

  • Technologies using fluorescence lifetime, including the Arno (compensation-free flow cytometry), Danube (direct fluorescence lifetime measurements) instruments, Colorado (automated autofluorescence removal), and Tiber (label-free cancer cell detection).
  • Extremely high-throughput flow cytometry (Loire).
  • Label-free flow cytometry (Yangtze).
  • Modular, customizable systems (Potomac).

Kinetic River’s Founder and President, Dr. Giacomo Vacca, is now inventor or coinventor on a total of 59 issued U.S. and international patents, as well as 18 pending as inventor or coinventor.

See all of Dr. Vacca’s patents →

Team & Board Updates

Sean Murphy Joins the Kinetic River Advisory Board

We are pleased to announce that Sean Murphy, CEO of SKMurphy, Inc., has joined the Kinetic River Advisory Board. His company, located in Silicon Valley, is a strategic advisory firm specializing in market creation and new technology product introduction.

Before starting SKMurphy, Sean worked for Cisco Systems, 3Com, and AMD in a variety of engineering management, marketing, and business development roles. He holds a BS in Mathematical Sciences and an MS in Engineering-Economic Systems from Stanford University.

Meet the entire Kinetic River Advisory Board →

Welcoming Hannu Lehtimäki to Kinetic River

We are pleased to share that Hannu Lehtimäki is now bringing his expertise to Kinetic River.

Hannu offers 30 years’ experience in development, support, management, and sales for CAD, knowledge-based engineering, product lifetime management, master data management, and enterprise resource planning. Hannu holds an M.Sc. in Engineering (Machine Design) from the Helsinki University of Technology.

Hannu will apply his expertise in mechanical and optomechanical design, leveraging the system design software he developed at BeamWise.

We look forward to working with Hannu on our various innovations!


Stay Updated on LinkedIn

Do you have a LinkedIn account? If so, we would like to keep you updated via that channel as well.

To start following our LinkedIn posts, you can click + Follow on the Kinetic River page.




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