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Pre-CYTO 2022 Newsletter

Pre-CYTO 2022 Newsletter

CYTO 2022 Preview and Latest Kinetic River News

With CYTO 2022 coming up fast, I want to share with you some of the latest news from Kinetic River and give you a preview of what we will be highlighting in Philadelphia.

One of the most exciting developments is the upcoming debut of our latest innovation, the Delaware Flow NanoCytometer™ for the sensitive detection of sub-micron particles, including extracellular vesicles and tumor-derived exosomes. We will also be introducing the Freedom Flow™ platform for compensation-free, autofluorescence-free, or label-free flow cytometry.

Keep reading to see more about what we have been up to and what you can expect from us at CYTO.

See you in Philly!

All the best,
Giacomo

 

Coming Up at CYTO 2022

Kinetic River Launches the Delaware Flow NanoCytometer™

We are proud to announce that we will be debuting our latest innovation, the Delaware Flow NanoCytometer at CYTO 2022. Based on our modular Potomac architecture, the Delaware was designed specifically for the sensitive detection of sub-micron particles, including extracellular vesicles (EVs) and tumor-derived exosomes in flow cytometry.

Stop by our booth and check it out in person. We hope to see you there.

The Delaware – see what you’ve been missing.

 

Kinetic River Announces the Freedom Flow™ Platform

Kinetic River will be introducing our new Freedom Flow platform at CYTO 2022. The platform, currently under development, consists of the Arno, for compensation-free flow cytometry, the Colorado, for autofluorescence-free flow cytometry, and the Tiber, for label-free flow cytometry. Freedom Flow also paves the way toward 40+ color flow cytometry.

If you want to see the latest developments, you will need to stop by our booth at CYTO. We hope to see you there.

Free up your workflow with Freedom Flow.

 

Dr. Alan Chin to Speak at CYTO

Monday June 6, come hear Kinetic River’s Dr. Alan Chin speak about our Arno analyzer and how our time-resolved flow cytometry (TRFC) technology enables compensation-free analysis. Dr. Chin’s talk is entitled “Analysis of a 12-Color Panel using a Compensation-Free Flow Cytometer with 6 Fluorescence Detectors”.

We will also be presenting a poster on our Colorado autofluorescence-free analyzer, part of our Freedom Flow platform. Stop by our poster “Automated Autofluorescence Removal in Flow Cytometry” to find out how we do it.

Our second poster, “The Delaware: A Flow NanoCytometer for Nanoparticle Analysis”, details some pretty impressive results from our new instrument which will make its debut at CYTO. Drop by our poster and see what it can do.

Check out the full program for CYTO 2022 →

 

Get Hands-On with Our Products at CYTO

Drop by our booth at CYTO to get an in-person look at some of our products:

  • The Shasta is our ultrastable Fluidics Control Module, suitable for the most demanding applications.
  • The Cavour is our always-on Flowcell Monitoring Module that allows you to see what’s going on in your flowcell without having to lift the cover.
  • The Tuolumne is a Quad Amplifier Module that gives you flexibility in customizing your instrument.

Also get familiar with our Panama data acquisition and visualization software. Custom-built from the ground up, we incorporated extensive user feedback to give you an intuitive, streamlined user interface. The Panama is at the heart of all of our instrumentation.

 

Latest Kinetic River Happenings

Kinetic River Receives Grant to Further Develop Its Colorado Platform

We’re thrilled to share that Kinetic River has been awarded an NIH Phase II SBIR grant from the National Institute of General Medical Sciences (NIGMS). This is our fifth SBIR award from NIH to date.

This $2.5M grant will allow us to continue development and our Colorado time-resolved technology to automatically remove autofluorescence background from flow cytometry measurements, facilitating cell analysis.

Come see the latest at our poster this year at CYTO.

Read the full press release here →

Thank you to Christopher Bare, Assistant Professor at the Icahn School of Medicine at Mount Sinai, and Pratip Chattopadhyay of Talon Biomarkers, who provided their enthusiastic perspectives on the technology.

Also many thanks to NIGMS and NIH for their continued support.

Image source: Monsel et al. (2014) PLoS ONE 9(3): e92564. doi:10.1371/journal.pone.0092564

 

Kinetic River is Issued its 15th Patent

Kinetic River was recently issued U.S. Patent No. 11,249,004, “Particle analysis and sorting apparatus and methods.”

This is our thirteenth U.S. patent, and, with one in China and one in Japan, our fifteenth overall. This patent further broadens our patent portfolio in the field of time-resolved flow cytometry.

For reference, our patents fit into the following families of intellectual property:

  1. Time-resolved technologies, including the Arno (compensation-free flow cytometry), Danube (direct fluorescence lifetime measurements) instruments, Colorado (automated autofluorescence removal), and Tiber (label-free cancer cell detection).
  2. Extremely high-throughput flow cytometry (Loire).
  3. Label-free flow cytometry (Yangtze).
  4. Modular, customizable systems (Potomac).

Congratulations to our President and Founder, Dr. Giacomo Vacca, who now holds 65 patents.

To view his full list of patents, visit his bio.

 

Kinetic River’s TRFC Technology Featured in Laser Focus World

Many thanks to Justine Murphy and Laser Focus World for a great interview and article on our time-resolved flow cytometry (TRFC) technology. TRFC is the technology behind Kinetic River’s Freedom Flow family of flow cytometers, enabling compensation-free, autofluorescence-free, and label-free flow cytometry.

To find out more about TRFC, download the article here →

 

Photo Gallery: The Making of a Potomac

Have you ever wondered what it takes to build a flow cytometer? We’ve put together a photo gallery showing the care and effort that goes into the making of one of our custom Potomac analyzers. The gallery takes you on the journey from a simple optical table to assembly of all components, and the careful packaging.

After we said “Bon voyage” to the instrument, we then installed it at the lab of Dr. Romeo Bernini at the Institute for the Electromagnetic Sensing of the Environment (IREA) of the National Research Council (CNR) in Naples, Italy. The lab there is using this custom instrument, which is designed to use  violet (405 nm), UV (375 nm), and deep-UV (266 nm) lasers, to excite autofluorescence in human cells for biomedical applications and in cyanobacteria to monitor water quality.

Check out the photo gallery →

Read the full narrative of the design and building of this instrument →

 

Employee Spotlight

Kinetic River Promotes Two Key Employees

Kinetic River is very pleased to announce the well-deserved promotions of two of our highly valued employees. Dr. Alan Chin, promoted to Principal Scientist, has been a key contributor to our development of innovative Flow Cytometry instrumentation. Ellie Gorina, now boasting the title of Office Manager, keeps Kinetic River running like a well-oiled machine through her many and varied contributions to the company.

Congratulations Alan and Ellie! We are lucky to have both of you on the team.

 

 

Stay Updated on LinkedIn

Do you have a LinkedIn account? If so, we would like to keep you updated via that channel as well.

To start following our LinkedIn posts, you can click + Follow on the Kinetic River page.

 

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